Background: Domestic violence (DV), including intimate partner violence (IPV), child abuse, and elder abuse, is a significant issue globally and in Ecuador. DV profoundly affects the mental and physical health of victims and perpetrators. Despite protective laws and support programs, viable and effective prevention strategies remain needed.

Objective: This study aimed to: 1) assess attitudes towards DV prevention among key actors (community leaders, healthcare providers, clergy, and NGO staff); 2) examine DV experiences and risk/protective factors in South Quito families; and 3) collaborate with community leaders to identify practical prevention interventions.

Methods: A Community-Based Participatory Research (CBPR) approach was used to engage key actors and recruit participants. A mixed-methods approach combined qualitative in-depth interviews (n=28) and a quantitative survey (n=203). Rapid Qualitative Analysis was used for qualitative data. Quantitative analysis included t-tests. Key actor perspectives and recommendations were further integrated through results sharing (member checking).

Results: Approximately 75% of female and 40% of male survey participants reported experiencing IPV, while 67% of older adults experienced elder abuse. Over 80% of participants used violent methods for disciplining children. Risk factors for IPV included childhood exposure to violence (92% exposed vs. 8% unexposed, p<0.001) and stress from financial insecurity (85% with stress vs. 15% without, p<0.005). A protective factor was having a partner who rarely or never binge-drinks alcohol (92% vs. 8%, p<0.001). Interviews and CBPR meetings revealed multiple uncoordinated prevention activities, including job training, psychological services, and school-based workshops. Recommendations included enhancing engagement across genders and ages, adopting a participatory framework, and fostering inter-institutional cooperation.

Discussion: DV remains a barrier to mental and physical health in South Quito. Prevention efforts are limited by poor awareness, access, and coordination. The CBPR approach facilitated better understanding and stronger relationships, essential for effective DV prevention programs.